Xenical

Definition

Xenical is the brand name for orlistat, a lipase inhibitor used to treat obesity. It works by preventing the absorption of fats from the diet, thus reducing caloric intake.

5 Must Know Facts For Your Next Test

1. Xenical is taken orally and is typically administered three times daily with each main meal containing fat.
2. The primary mechanism of action involves inhibition of gastric and pancreatic lipases, enzymes responsible for breaking down dietary fats.
3. Common side effects include gastrointestinal issues such as oily stools, flatulence, and frequent bowel movements due to unabsorbed fat.
4. It is recommended to take a multivitamin supplement while on Xenical because it can reduce the absorption of fat-soluble vitamins (A, D, E, and K).
5. Xenical is often prescribed as part of a comprehensive weight management program that includes a reduced-calorie diet and physical activity.

Review Questions

• What enzyme does Xenical inhibit to prevent fat absorption?
• Why might patients taking Xenical be advised to use multivitamin supplements?
• What are some common gastrointestinal side effects associated with Xenical?

Related terms

Orlistat: The generic name for Xenical.

Lipase Inhibitors: A class of drugs that prevent the breakdown and absorption of dietary fats.

Fat-Soluble Vitamins: Vitamins A, D, E, and K which require dietary fat for proper absorption.