Vinblastine

Definition

Vinblastine is a chemotherapy drug that inhibits the assembly of microtubules, effectively stopping cell division. It is primarily used for treating various types of cancer including Hodgkin's lymphoma and testicular cancer.

5 Must Know Facts For Your Next Test

1. Vinblastine works by binding to tubulin and inhibiting microtubule formation, arresting cells in metaphase.
2. It is classified as a vinca alkaloid and derived from the periwinkle plant.
3. Common side effects include bone marrow suppression, hair loss, and nausea.
4. Vinblastine is often administered intravenously in a clinical setting.
5. Monitoring of blood counts is essential during treatment to manage potential myelosuppression.

Review Questions

• What mechanism does Vinblastine use to inhibit cancer cell division?
• Name two types of cancer that Vinblastine is commonly used to treat.
• What are some common side effects associated with Vinblastine treatment?

Related terms

Vinca Alkaloids: A class of anti-mitotic drugs derived from the periwinkle plant, used in cancer therapy.

Microtubule Inhibitors: Drugs that interfere with microtubule function, crucial for cell division.

Myelosuppression: A reduction in bone marrow activity leading to decreased production of blood cells.