Tybost

Definition

Tybost is a pharmacokinetic enhancer used in combination with certain antiretroviral drugs to treat HIV-1 infection. It works by inhibiting enzymes that metabolize these drugs, thereby increasing their effectiveness.

5 Must Know Facts For Your Next Test

1. Tybost contains the active ingredient cobicistat.
2. It is primarily used to boost the levels of atazanavir and darunavir.
3. Tybost does not have direct antiviral activity against HIV-1.
4. It can cause side effects such as jaundice and elevated liver enzymes.
5. Cobicistat, the main component of Tybost, is a potent inhibitor of CYP3A enzymes.

Review Questions

• What is the primary function of Tybost in HIV treatment?
• Which active ingredient is found in Tybost?
• Name two antiretroviral drugs that are commonly boosted by Tybost.

Related terms

Antiretroviral: Drugs used to prevent or treat HIV/AIDS by inhibiting the virus's ability to replicate.

Atazanavir: An antiretroviral drug often boosted by Tybost to increase its effectiveness.

CYP3A Inhibitors: A class of drugs that inhibit the enzyme CYP3A, affecting the metabolism of many medications including antiretrovirals.