Trientine
from class: Pharmacology for Nurses Definition Trientine is a chelating agent used primarily to treat Wilson's disease by binding copper, allowing it to be excreted from the body. It is an alternative for patients who cannot tolerate penicillamine.
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Predict what's on your test 5 Must Know Facts For Your Next Test Trientine is indicated for the treatment of Wilson's disease, a genetic disorder causing copper accumulation. The drug works by chelating copper, facilitating its excretion through urine. Trientine should be taken on an empty stomach to enhance absorption. Common side effects include gastrointestinal disturbances and iron deficiency anemia. Patients using trientine should avoid taking iron supplements or antacids concurrently as they can interfere with the medication's efficacy. Review Questions What is the primary use of trientine in clinical practice? How does trientine facilitate the removal of excess copper from the body? Why should trientine be taken on an empty stomach?
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