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Trazodone hydrochloride

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Pharmacology for Nurses

Definition

Trazodone hydrochloride is an antidepressant medication commonly used to treat major depressive disorder. It also has sedative properties and is sometimes prescribed for insomnia.

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5 Must Know Facts For Your Next Test

  1. Trazodone works by inhibiting the reuptake of serotonin, thereby increasing its levels in the brain.
  2. It is classified as a serotonin antagonist and reuptake inhibitor (SARI).
  3. Common side effects include drowsiness, dizziness, dry mouth, and blurred vision.
  4. Trazodone can interact with other medications like MAO inhibitors and should not be combined with them.
  5. Patients are advised to take trazodone after a meal or snack to increase absorption and reduce gastrointestinal side effects.

Review Questions

  • What class of drugs does trazodone hydrochloride belong to?
  • What are some common side effects of trazodone?
  • Why should trazodone not be combined with MAO inhibitors?

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