Transmission

Definition

Transmission in pharmacology refers to the process by which pain signals are relayed from peripheral nerves to the central nervous system. This involves neurotransmitters and synaptic pathways.

5 Must Know Facts For Your Next Test

1. Transmission of pain signals primarily occurs through afferent nerve fibers.
2. Neurotransmitters like glutamate and substance P play crucial roles in transmitting pain signals.
3. The dorsal horn of the spinal cord is a key site for the modulation of pain transmission.
4. Inhibitory neurotransmitters such as GABA can modulate or dampen the transmission of pain signals.
5. Effective pain management often involves drugs that interfere with specific stages of pain transmission.

Review Questions

• What role do neurotransmitters play in the transmission of pain signals?
• How does inhibition at the dorsal horn affect pain transmission?
• Name two key neurotransmitters involved in the transmission phase of nociception.

Related terms

Nociception:

The sensory process that provides signals leading to the perception of pain.

Afferent Nerve Fibers: Nerves that carry sensory signals from receptors to the central nervous system.

Synapse:

The junction between two neurons where information is transmitted from one neuron to another.