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Taxol

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Pharmacology for Nurses

Definition

Taxol, also known as paclitaxel, is a chemotherapeutic drug used to treat various cancers by inhibiting cell division. It stabilizes microtubules and prevents them from breaking down, which is essential for cell replication.

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5 Must Know Facts For Your Next Test

  1. Taxol is derived from the bark of the Pacific yew tree.
  2. It is commonly used to treat ovarian, breast, lung, pancreatic, and other types of cancer.
  3. Taxol works by stabilizing microtubules and preventing their depolymerization during mitosis.
  4. It can cause side effects such as neutropenia, neuropathy, and hypersensitivity reactions.
  5. Taxol is often administered intravenously in combination with other chemotherapy drugs.

Review Questions

  • What is the primary mechanism of action for Taxol?
  • Which types of cancer are commonly treated with Taxol?
  • What are some common side effects associated with Taxol?

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