Stellara is a biologic medication used to treat moderate to severe plaque psoriasis and psoriatic arthritis. It works by targeting specific proteins in the immune system to reduce inflammation and slow the overproduction of skin cells.
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Stellara targets interleukin-12 (IL-12) and interleukin-23 (IL-23) cytokines, which play a key role in the inflammatory process.
It is administered via subcutaneous injection, typically every 12 weeks after initial doses at weeks 0 and 4.
Common side effects include upper respiratory infections, headache, and fatigue.
Patients need to be screened for tuberculosis before starting Stellara therapy due to the risk of infection.
Stellara has shown efficacy in reducing the symptoms of both skin lesions and joint pain in patients with psoriatic arthritis.
Review Questions
What cytokines does Stellara target in the treatment of psoriasis?
How is Stellara administered, and what is its dosing schedule?
What are some common side effects associated with Stellara?
Related terms
Cytokine: A type of protein important in cell signaling involved in immune responses.
Plaque Psoriasis: A chronic autoimmune condition characterized by red, scaly patches on the skin.
Biologic Medication: Drugs derived from living organisms used to treat various medical conditions by targeting specific components of the immune system.