Pseudoephedrine

Definition

Pseudoephedrine is an oral decongestant commonly used to relieve nasal congestion caused by colds, allergies, or hay fever. It works by shrinking the blood vessels in the nasal passages.

5 Must Know Facts For Your Next Test

1. Pseudoephedrine can elevate blood pressure and should be used with caution in patients with hypertension.
2. It is a sympathomimetic amine that primarily acts on alpha-adrenergic receptors to produce vasoconstriction.
3. Common side effects include insomnia, nervousness, and dizziness.
4. Pseudoephedrine is regulated under the Combat Methamphetamine Epidemic Act due to its use in methamphetamine production.
5. It should not be taken concurrently with monoamine oxidase inhibitors (MAOIs) due to the risk of hypertensive crisis.

Review Questions

• What are the primary actions of pseudoephedrine on nasal passages?
• Why must pseudoephedrine be used cautiously in patients with high blood pressure?
• What regulation affects the sale of pseudoephedrine-containing products?

Related terms

Antihistamines:

Medications that block histamine receptors to reduce allergy symptoms.

Decongestants:

Drugs designed to relieve nasal congestion by reducing swelling in the nasal passages.

Cerumenolytics:

Agents used to soften and break down earwax for easier removal.