Phenelzine sulfate

Definition

Phenelzine sulfate is a monoamine oxidase inhibitor (MAOI) used to treat major depressive disorder. It works by increasing the levels of certain chemicals in the brain that help elevate mood.

5 Must Know Facts For Your Next Test

1. Phenelzine sulfate can interact dangerously with tyramine-rich foods, causing hypertensive crises.
2. Common side effects include dizziness, drowsiness, and weight gain.
3. Patients taking phenelzine sulfate should avoid other medications like SSRIs and certain pain relievers due to risk of serotonin syndrome.
4. The therapeutic effects of phenelzine sulfate may take several weeks to become apparent.
5. It is essential for patients to inform healthcare providers about phenelzine use before undergoing any surgical procedures.

Review Questions

• What class of antidepressants does phenelzine sulfate belong to?
• Why must patients taking phenelzine sulfate avoid foods high in tyramine?
• What serious condition can occur if phenelzine sulfate is taken with SSRIs?

Related terms

Monoamine Oxidase Inhibitors (MAOIs): A class of antidepressant drugs that work by inhibiting the action of monoamine oxidase enzymes.

Serotonin Syndrome: A potentially life-threatening condition caused by excessive accumulation of serotonin in the central nervous system.

Hypertensive Crisis: A severe increase in blood pressure that can lead to stroke or other severe complications, often triggered by interactions with certain foods or medications when taking MAOIs.