Pharmacology for Nurses

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Pharmacogenetics

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Pharmacology for Nurses

Definition

Pharmacogenetics is the study of how an individual's genetic makeup affects their response to drugs. This field aims to personalize medication therapy based on genetic profiles.

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5 Must Know Facts For Your Next Test

  1. Pharmacogenetics can help predict adverse drug reactions and improve drug efficacy.
  2. It involves analyzing specific genes that encode drug-metabolizing enzymes, transporters, and receptors.
  3. Commonly studied genes in pharmacogenetics include CYP2D6, CYP2C19, and TPMT.
  4. Pharmacogenetic testing can guide dosage adjustments for drugs like warfarin and antidepressants.
  5. Understanding pharmacogenetics is crucial for tailoring treatments in populations with diverse genetic backgrounds.

Review Questions

  • What is the primary goal of pharmacogenetics?
  • Which genes are commonly analyzed in pharmacogenetic studies?
  • How does pharmacogenetics contribute to personalized medicine?

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