Pegfilgrastim
from class: Pharmacology for Nurses Definition Pegfilgrastim is a long-acting form of filgrastim, a granulocyte colony-stimulating factor (G-CSF) that stimulates the production of neutrophils. It is used to decrease the incidence of infection in patients undergoing chemotherapy.
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Predict what's on your test 5 Must Know Facts For Your Next Test Pegfilgrastim is administered as a subcutaneous injection, typically once per chemotherapy cycle. It helps reduce the risk of febrile neutropenia by increasing the number of white blood cells. The drug is often given 24 hours after chemotherapy completion to optimize its effectiveness. Common side effects include bone pain and redness at the injection site. Pegfilgrastim has a polyethylene glycol (PEG) component which increases its half-life compared to filgrastim. Review Questions What is the primary function of pegfilgrastim in cancer therapy? How does pegfilgrastim differ from filgrastim in terms of administration frequency? What are common side effects associated with pegfilgrastim?
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