Peak

Definition

Peak refers to the highest concentration of a drug in the bloodstream after administration. It indicates the point at which the medication is most effective.

5 Must Know Facts For Your Next Test

1. The peak level is crucial for determining the efficacy and safety of a drug.
2. Peak levels are typically measured through blood tests at specific times after drug administration.
3. The time to reach peak concentration can vary based on the route of administration (e.g., oral, intravenous).
4. Monitoring peak levels helps prevent toxicity by ensuring that concentrations do not exceed therapeutic ranges.
5. Differences in patient metabolism can affect how quickly or slowly a drug reaches its peak.

Review Questions

• What does the term 'peak' signify in pharmacokinetics?
• Why is it important to monitor peak levels of a medication?
• How can the route of administration influence the time to reach peak concentration?

Related terms

Trough Level: The lowest concentration of a drug in the bloodstream before the next dose.

Half-life: The time it takes for half of the drug to be eliminated from the body.

Therapeutic Range: The range of drug concentrations in which a medication is effective without being toxic.