Pharmacology for Nurses

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Octreotide

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Pharmacology for Nurses

Definition

Octreotide is a synthetic analog of somatostatin used to treat severe diarrhea associated with certain gastrointestinal disorders. It works by inhibiting the release of various hormones and reducing gastrointestinal fluid secretion.

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5 Must Know Facts For Your Next Test

  1. Octreotide is commonly used to manage symptoms in patients with carcinoid tumors and VIPomas, which can cause severe diarrhea.
  2. It is administered via subcutaneous or intravenous injection due to poor oral bioavailability.
  3. Common side effects include abdominal pain, nausea, and injection site reactions.
  4. Octreotide can also reduce blood flow to the gastrointestinal tract, helping to control bleeding from varices in cirrhotic patients.
  5. The drug mimics natural somatostatin but has a longer half-life, making it more effective for sustained symptom management.

Review Questions

  • What are the primary indications for using Octreotide?
  • How is Octreotide administered and why?
  • What are some common side effects associated with Octreotide use?

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