Nonselective alpha- and beta-adrenergic agonists stimulate both alpha and beta adrenergic receptors, leading to widespread effects on the cardiovascular and respiratory systems. They are often used in emergency situations to manage severe asthma attacks or anaphylaxis.
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They can increase heart rate and blood pressure due to their action on alpha-1 and beta-1 receptors.
They cause bronchodilation by stimulating beta-2 receptors, making them useful in treating bronchospasm.
Common nonselective alpha- and beta-adrenergic agonists include epinephrine and norepinephrine.
Side effects can include anxiety, tremors, palpitations, hypertension, and arrhythmias.
Due to their potent effects, they are typically administered in controlled settings like hospitals during emergencies.
Review Questions
What physiological responses are triggered by nonselective alpha- and beta-adrenergic agonists?
Name two common drugs that act as nonselective alpha- and beta-adrenergic agonists.
Why must the administration of nonselective alpha- and beta-adrenergic agonists be closely monitored?
Related terms
Selective Beta2-Adrenergic Agonist: Drugs that specifically target beta2 receptors to induce bronchodilation with fewer cardiovascular side effects.
Anticholinergic: Drugs that block acetylcholine receptors to reduce parasympathetic nerve impulses, often used for bronchodilation.
Adrenergic Receptor: Receptors that respond to adrenaline (epinephrine) or noradrenaline (norepinephrine), playing a key role in the fight-or-flight response.
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