Netarsudil
from class: Pharmacology for Nurses Definition Netarsudil is an ophthalmic solution used to reduce intraocular pressure in patients with open-angle glaucoma or ocular hypertension. It works by inhibiting Rho kinase, which increases the outflow of aqueous humor through the trabecular meshwork.
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Predict what's on your test 5 Must Know Facts For Your Next Test Netarsudil is typically administered as a 0.02% ophthalmic solution once daily in the evening. Common side effects include conjunctival hyperemia, corneal verticillata, and eye pain. It can be used alone or in combination with other antiglaucoma medications. Netarsudil's mechanism of action involves increasing trabecular outflow and decreasing episcleral venous pressure. Patients should be advised to remove contact lenses before administration and wait at least 15 minutes before reinserting them. Review Questions What is the primary therapeutic use of netarsudil? Describe the mechanism of action for netarsudil in lowering intraocular pressure. List two common side effects associated with netarsudil.
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