Nadolol

Definition

Nadolol is a non-selective beta-adrenergic blocker used primarily for the management of hypertension and angina pectoris. It decreases heart rate and myocardial oxygen demand, providing relief from cardiac symptoms.

5 Must Know Facts For Your Next Test

1. Nadolol blocks both beta-1 and beta-2 adrenergic receptors.
2. It is commonly prescribed for high blood pressure (hypertension) and chest pain (angina).
3. Nadolol has a long half-life, allowing for once-daily dosing.
4. Potential side effects include bradycardia, hypotension, and fatigue.
5. Patients with asthma or chronic obstructive pulmonary disease (COPD) should use nadolol cautiously due to its non-selective action.

Review Questions

• What types of receptors does nadolol block?
• Why might nadolol be contraindicated in patients with respiratory conditions like asthma?
• List two primary clinical uses of nadolol.

Related terms

Propranolol:

A non-selective beta-blocker used to treat hypertension and angina.

Metoprolol:

A selective beta-1 blocker mainly used for treating hypertension and angina.

Beta-Adrenergic Receptors:

Receptors that are targets for beta-blockers, involved in regulating heart rate and vascular tone.