Motrin is a brand name for the drug ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, reduce inflammation, and lower fever. It works by inhibiting the enzyme cyclooxygenase (COX), which decreases the formation of prostaglandins involved in pain and inflammation.
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Motrin is commonly used for mild to moderate pain such as headaches, dental pain, menstrual cramps, muscle aches, or arthritis.
It can cause gastrointestinal side effects like ulcers and bleeding; therefore, it should be taken with food or milk.
Motrin has both analgesic and antipyretic properties, making it effective for reducing fever as well as pain.
Contraindications include patients with known hypersensitivity to ibuprofen or other NSAIDs, and those with conditions like severe heart failure or active peptic ulcer disease.
The maximum recommended daily dose for adults is generally 3200 mg, divided into several doses.
Review Questions
What is the mechanism of action for Motrin in alleviating pain?
List potential gastrointestinal side effects of taking Motrin.
Why might Motrin be contraindicated in patients with certain cardiovascular conditions?
Related terms
Ibuprofen: The generic name for Motrin, an NSAID used to treat pain and inflammation.
Prostaglandins: Lipid compounds that are involved in injury and illness processes such as inflammation and blood clotting.
Cyclooxygenase (COX): An enzyme that converts arachidonic acid into prostaglandins; inhibited by NSAIDs like ibuprofen.