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Monoamine

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Pharmacology for Nurses

Definition

Monoamines are neurotransmitters that include serotonin, dopamine, norepinephrine, and epinephrine. They play a crucial role in regulating mood, emotion, and arousal.

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5 Must Know Facts For Your Next Test

  1. Monoamine oxidase inhibitors (MAOIs) are a class of antidepressants that work by inhibiting the breakdown of monoamines.
  2. Selective serotonin reuptake inhibitors (SSRIs) increase the level of serotonin in the brain by preventing its reabsorption into neurons.
  3. Imbalances in monoamine levels are linked to various psychiatric conditions such as depression and anxiety.
  4. Common side effects of drugs affecting monoamines include nausea, insomnia, and sexual dysfunction.
  5. Monoamines are synthesized from amino acids like tryptophan (serotonin) and tyrosine (dopamine and norepinephrine).

Review Questions

  • What role do monoamines play in mood regulation?
  • How do MAOIs affect monoamine levels in the brain?
  • What is a common side effect of SSRIs?

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