Mestinon is a brand name for pyridostigmine, a medication that inhibits acetylcholinesterase to improve muscle strength in patients with myasthenia gravis. It increases the levels of acetylcholine at neuromuscular junctions, enhancing communication between nerves and muscles.
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Mestinon is primarily used to treat myasthenia gravis by improving muscle contraction.
It works by inhibiting the enzyme acetylcholinesterase, preventing the breakdown of acetylcholine.
Common side effects include nausea, diarrhea, abdominal cramps, and increased salivation.
Dosage must be carefully adjusted based on individual response and symptom severity.
Mestinon can also be used as an antidote for certain types of nerve agent poisoning.
Review Questions
What is the primary mechanism of action for Mestinon?
List three common side effects associated with Mestinon use.
How does Mestinon help improve symptoms in myasthenia gravis patients?
Related terms
Myasthenia Gravis: An autoimmune disorder characterized by weakness and rapid fatigue of voluntary muscles.
Acetylcholinesterase Inhibitors: A class of drugs that prevent the breakdown of acetylcholine, enhancing cholinergic neurotransmission.
Cholinergic Crisis: A condition caused by excessive accumulation of acetylcholine due to overmedication with acetylcholinesterase inhibitors, leading to muscle weakness and respiratory failure.