Lipase inhibitors

Definition

Lipase inhibitors are medications that block the action of lipase, an enzyme responsible for breaking down dietary fats in the digestive system. This inhibition prevents fat absorption, leading to weight loss.

5 Must Know Facts For Your Next Test

1. Lipase inhibitors reduce the absorption of dietary fats by about 30%.
2. Orlistat is a commonly prescribed lipase inhibitor for weight management.
3. Patients taking lipase inhibitors may experience side effects such as oily stools and flatulence.
4. These inhibitors are often used in conjunction with a reduced-calorie diet and exercise for effective weight loss.
5. Lipase inhibitors can interfere with the absorption of fat-soluble vitamins (A, D, E, K), necessitating supplementation.

Review Questions

• What is the primary function of lipase inhibitors in weight management?
• Name a commonly prescribed lipase inhibitor used for weight reduction.
• What potential side effect might patients experience when taking lipase inhibitors?

Related terms

Orlistat: A lipase inhibitor medication used to treat obesity.

Fat-soluble vitamins: Vitamins A, D, E, and K that require dietary fat for proper absorption.

Dietary fat: Fats consumed in food that are broken down by enzymes like lipase during digestion.