Lipase

Definition

Lipase is an enzyme that catalyzes the breakdown of fats into fatty acids and glycerol. It plays a crucial role in the digestive process, especially within the small intestine.

5 Must Know Facts For Your Next Test

1. Lipases are primarily produced in the pancreas and secreted into the small intestine.
2. They are essential for the proper digestion and absorption of dietary fats.
3. Orlistat is a weight management drug that inhibits pancreatic lipase, reducing fat absorption.
4. Lipase activity can be measured to diagnose pancreatitis or other pancreatic disorders.
5. Inhibiting lipase can lead to side effects like steatorrhea (excess fat in feces).

Review Questions

• What is the primary function of lipase in the digestive system?
• Which organ produces and secretes most of the body's lipase?
• How does Orlistat affect lipase activity?

Related terms

Amylase:

An enzyme that catalyzes the breakdown of starches into sugars.

Protease: An enzyme that breaks down proteins into smaller peptides or amino acids.

Orlistat:

A weight management drug that inhibits pancreatic lipases, reducing fat absorption.