Linezolid

Definition

Linezolid is an antibiotic used to treat infections caused by Gram-positive bacteria, including resistant strains like MRSA. It belongs to the oxazolidinone class of drugs and works by inhibiting bacterial protein synthesis.

5 Must Know Facts For Your Next Test

1. Linezolid is effective against Gram-positive bacteria, including MRSA and VRE.
2. It can be administered both orally and intravenously.
3. Common side effects include diarrhea, headache, and nausea.
4. Prolonged use can lead to serious side effects like bone marrow suppression and peripheral neuropathy.
5. Linezolid has a unique mechanism of action that involves inhibition of the bacterial ribosome.

Review Questions

• What types of bacteria is Linezolid primarily effective against?
• List two common side effects of Linezolid.
• What is the mechanism of action for Linezolid?

Related terms

MRSA: Methicillin-resistant Staphylococcus aureus, a type of bacteria resistant to many antibiotics.

VRE: Vancomycin-resistant Enterococci, a type of bacteria that has developed resistance to vancomycin.

Oxazolidinones: A class of synthetic antibiotics that inhibit bacterial protein synthesis.