Leukopenia

Definition

Leukopenia is a condition characterized by a reduced number of white blood cells (WBCs) in the blood, making the body more susceptible to infections. It is a common side effect of chemotherapeutic drugs used in cancer therapy.

5 Must Know Facts For Your Next Test

1. Leukopenia increases the risk of infections due to weakened immune response.
2. Common chemotherapeutic agents that cause leukopenia include cyclophosphamide and methotrexate.
3. Patients with leukopenia may require prophylactic antibiotics to prevent infections.
4. Regular monitoring of white blood cell count is essential for patients undergoing chemotherapy.
5. Symptoms of leukopenia can include fever, chills, and frequent infections.

Review Questions

• What are the primary risks associated with leukopenia?
• Name two chemotherapeutic drugs that commonly cause leukopenia.
• Why is it important to monitor white blood cell counts in patients receiving chemotherapy?

Related terms

Neutropenia:

A specific type of leukopenia involving a low number of neutrophils, which are crucial for fighting bacterial infections.

Myelosuppression:

A decrease in bone marrow activity resulting in reduced production of blood cells, including WBCs.

Granulocyte Colony-Stimulating Factor (G-CSF): A medication that stimulates the bone marrow to produce more white blood cells, often used to treat or prevent leukopenia during chemotherapy.