Kytril

Definition

Kytril is the brand name for granisetron, an antiemetic used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, and surgery. It works by blocking serotonin receptors in the brain and gastrointestinal tract.

5 Must Know Facts For Your Next Test

1. Kytril is commonly administered orally or via intravenous injection.
2. It specifically targets the 5-HT3 receptors to prevent nausea and vomiting.
3. Kytril is effective in both acute and delayed phases of chemotherapy-induced nausea.
4. Possible side effects include headache, constipation, and asthenia (weakness).
5. Dosage adjustments may be necessary for patients with severe hepatic impairment.

Review Questions

• How does Kytril work to prevent nausea and vomiting?
• What are common side effects associated with Kytril?
• Why might dosage adjustments be necessary for patients taking Kytril?

Related terms

Ondansetron: An antiemetic that also blocks serotonin receptors to prevent nausea and vomiting.

Metoclopramide: A medication used to treat nausea that enhances gastrointestinal motility.

Dolasetron: Another serotonin receptor antagonist used as an antiemetic in cancer therapy.