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JULUCA

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Pharmacology for Nurses

Definition

Juluca is a combination antiretroviral medication that contains dolutegravir and rilpivirine. It is used for the maintenance treatment of HIV-1 infection in adults who are virologically suppressed.

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5 Must Know Facts For Your Next Test

  1. Juluca consists of two active ingredients: dolutegravir, an integrase strand transfer inhibitor (INSTI), and rilpivirine, a non-nucleoside reverse transcriptase inhibitor (NNRTI).
  2. It is prescribed for patients with HIV-1 who have been on a stable antiretroviral regimen for at least six months and have no history of treatment failure.
  3. Juluca should be taken once daily with a meal to ensure proper absorption.
  4. Common side effects include headache, diarrhea, and changes in liver enzymes; more severe side effects may include depressive disorders and hepatotoxicity.
  5. Patients should undergo regular monitoring of viral load, CD4 count, and potential drug interactions while on Juluca.

Review Questions

  • What are the two active components of Juluca?
  • For which patient population is Juluca indicated?
  • What are some common side effects associated with Juluca?

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