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Haloperidol

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Pharmacology for Nurses

Definition

Haloperidol is a first-generation antipsychotic used primarily to treat schizophrenia and acute psychosis. It works by blocking dopamine receptors in the brain.

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5 Must Know Facts For Your Next Test

  1. Haloperidol can cause extrapyramidal side effects, such as tardive dyskinesia.
  2. Commonly administered via oral, intramuscular, or intravenous routes.
  3. It is often used in emergency settings for rapid sedation of agitated patients.
  4. Haloperidol has a high affinity for D2 dopamine receptors, which underlies its therapeutic and side effect profile.
  5. It is contraindicated in patients with Parkinson's disease due to its dopamine-blocking effects.

Review Questions

  • What are the primary uses of Haloperidol?
  • What are the common side effects associated with Haloperidol?
  • Why is Haloperidol contraindicated in patients with Parkinson's disease?
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