Glyburide

Definition

Glyburide is an oral antidiabetic drug used to control blood sugar levels in patients with type 2 diabetes. It belongs to the class of drugs known as sulfonylureas, which stimulate insulin release from pancreatic beta cells.

5 Must Know Facts For Your Next Test

1. Glyburide is typically taken once or twice a day with meals to reduce the risk of hypoglycemia.
2. It works by stimulating the pancreas to produce more insulin, which helps lower blood glucose levels.
3. Common side effects include hypoglycemia, weight gain, and gastrointestinal disturbances.
4. Glyburide is contraindicated in patients with type 1 diabetes or diabetic ketoacidosis.
5. Patients should be monitored for signs of hypoglycemia, especially when initiating therapy or adjusting dosage.

Review Questions

• What class of drugs does Glyburide belong to?
• What is the primary mechanism of action for Glyburide?
• Why should Glyburide not be used in patients with type 1 diabetes?

Related terms

Sulfonylureas: A class of oral antidiabetic drugs that stimulate insulin secretion from pancreatic beta cells.

Hypoglycemia: A condition characterized by abnormally low blood glucose levels, often a side effect of antidiabetic medications.

Type 2 Diabetes: A chronic condition that affects the way the body processes blood sugar (glucose), commonly managed with diet, exercise, and medication like Glyburide.