Gemzar
from class: Pharmacology for Nurses Definition Gemzar, also known as gemcitabine, is a nucleoside analog used as an antineoplastic (chemotherapy) agent. It interferes with DNA synthesis, inhibiting the growth of cancer cells.
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Predict what's on your test 5 Must Know Facts For Your Next Test Gemzar is primarily used in the treatment of pancreatic, lung, breast, and ovarian cancers. It is administered intravenously and often combined with other chemotherapy agents for greater efficacy. Common side effects include nausea, vomiting, low blood counts, and fatigue. Gemcitabine works by incorporating itself into the DNA of cancer cells during replication, causing cell death. Dosage adjustments may be necessary for patients with hepatic or renal impairment. Review Questions What types of cancer is Gemzar commonly used to treat? How does Gemzar interfere with the replication of cancer cells? What are common side effects associated with Gemzar?
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