Gemcitabine
from class:
Pharmacology for Nurses
Definition
Gemcitabine is a nucleoside analog used as chemotherapy. It inhibits DNA synthesis, causing cell death in rapidly dividing cancer cells.
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5 Must Know Facts For Your Next Test
- Gemcitabine is primarily used to treat pancreatic, lung, breast, and ovarian cancers.
- It is typically administered intravenously.
- Common side effects include nausea, vomiting, and myelosuppression.
- Gemcitabine works by incorporating itself into the DNA of cancer cells, leading to apoptosis.
- It is often used in combination with other chemotherapeutic agents for enhanced efficacy.
Review Questions
- What types of cancer are commonly treated with Gemcitabine?
- How does Gemcitabine work at the cellular level?
- What are some common side effects associated with Gemcitabine?
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