Fluticasone

Definition

Fluticasone is a synthetic corticosteroid used to reduce inflammation in the airways, commonly prescribed for asthma and chronic obstructive pulmonary disease (COPD). It works by inhibiting multiple types of inflammatory cells and decreasing the production of mediators involved in the inflammatory response.

5 Must Know Facts For Your Next Test

1. Fluticasone is available in various forms including inhalers, nasal sprays, and topical creams.
2. It has a high first-pass metabolism, meaning it is extensively metabolized in the liver after oral administration.
3. Common side effects include throat irritation, hoarseness, and oral thrush when used as an inhaler.
4. Patients should rinse their mouths after using fluticasone inhalers to prevent oral thrush.
5. It does not provide immediate relief of acute bronchospasm; instead, it is used for long-term management.

Review Questions

• What are the different forms in which fluticasone is available?
• Why should patients rinse their mouths after using a fluticasone inhaler?
• Name two common side effects of using fluticasone as an inhaler.

Related terms

Corticosteroids: A class of steroid hormones that reduce inflammation and suppress the immune system.

Asthma: A chronic respiratory condition characterized by airway inflammation and hyperreactivity.

Chronic Obstructive Pulmonary Disease (COPD): A group of lung diseases that block airflow and make breathing difficult.