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Estropipate

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Pharmacology for Nurses

Definition

Estropipate is a synthetic estrogen used in hormone replacement therapy to manage menopausal symptoms and prevent osteoporosis. It works by compensating for the decreased estrogen levels in postmenopausal women.

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5 Must Know Facts For Your Next Test

  1. Estropipate is commonly prescribed for managing hot flashes, vaginal dryness, and other menopausal symptoms.
  2. It is also used to prevent osteoporosis in postmenopausal women by maintaining bone density.
  3. Like other estrogens, estropipate can increase the risk of endometrial cancer if not taken with a progestin in women with an intact uterus.
  4. Common side effects include nausea, breast tenderness, and headache.
  5. Estropipate is contraindicated in women with a history of thromboembolic disorders or hormone-sensitive cancers.

Review Questions

  • What are the primary uses of estropipate in postmenopausal women?
  • Why must estropipate be taken with caution in patients with a history of thromboembolic disorders?
  • What are some common side effects associated with taking estropipate?

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