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Estrace

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Pharmacology for Nurses

Definition

Estrace is a brand name for estradiol, a form of estrogen used to treat symptoms of menopause such as hot flashes and vaginal dryness. It is also utilized in hormone replacement therapy (HRT) and sometimes in the treatment of certain types of infertility.

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5 Must Know Facts For Your Next Test

  1. Estrace is primarily prescribed for menopausal symptom relief, including vasomotor symptoms (hot flashes) and urogenital atrophy.
  2. It can be administered orally or topically; the route depends on the specific condition being treated.
  3. Common side effects include nausea, headache, breast tenderness, and irregular vaginal bleeding.
  4. Contraindications include a history of thromboembolic disorders, liver dysfunction, and estrogen-dependent tumors.
  5. When used for infertility treatments, Estrace helps prepare the uterine lining for embryo implantation.

Review Questions

  • What are the primary uses of Estrace in clinical practice?
  • List three common side effects associated with Estrace use.
  • Why is Estrace contraindicated in patients with a history of thromboembolic disorders?

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