Emend
from class: Pharmacology for Nurses Definition Emend is a brand name for aprepitant, a medication used to prevent nausea and vomiting caused by chemotherapy and surgery. It works by blocking neurokinin-1 (NK1) receptors in the brain.
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Predict what's on your test 5 Must Know Facts For Your Next Test Emend is often used in combination with other antiemetics like ondansetron and dexamethasone. It is administered orally or intravenously, typically starting one hour before chemotherapy. Common side effects include fatigue, hiccups, and gastrointestinal issues such as diarrhea or constipation. Emend's effectiveness can be influenced by CYP3A4 enzyme interactions; it may require dosage adjustments when taken with certain medications. It is not recommended for use during pregnancy unless absolutely necessary due to potential risks. Review Questions What class of drug does Emend belong to? What are common side effects of Emend? How does Emend interact with other medications metabolized by CYP3A4?
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