Dutasteride
from class: Pharmacology for Nurses Definition Dutasteride is a medication used to treat benign prostatic hyperplasia (BPH) in men by inhibiting the enzyme 5-alpha-reductase. This action decreases the production of dihydrotestosterone (DHT), which contributes to prostate growth.
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Predict what's on your test 5 Must Know Facts For Your Next Test Dutasteride is a 5-alpha-reductase inhibitor that reduces levels of DHT. It is commonly prescribed for symptoms of an enlarged prostate, such as difficulty urinating. The medication may take several months to show significant effects on prostate size and urinary symptoms. Common side effects include decreased libido, erectile dysfunction, and ejaculation disorders. Dutasteride is contraindicated in women and children and should not be handled by pregnant women due to risk of teratogenicity. Review Questions What enzyme does dutasteride inhibit and what is the result? List two common side effects associated with dutasteride use. Why should dutasteride not be handled by pregnant women?
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