Diphenoxylate with atropine

Definition

Diphenoxylate with atropine is a combination medication used to treat acute and chronic diarrhea. It works by slowing intestinal movement and reducing bowel frequency.

5 Must Know Facts For Your Next Test

1. Diphenoxylate is an opioid agonist, whereas atropine is included to discourage abuse of the medication.
2. Common side effects include drowsiness, dizziness, and dry mouth.
3. It is contraindicated in patients with obstructive jaundice or diarrhea caused by pseudomembranous enterocolitis.
4. The usual dosage for adults is initially 5 mg four times daily until control is achieved.
5. Prolonged use can lead to dependence due to the opioid nature of diphenoxylate.

Review Questions

• What are the primary components of Diphenoxylate with atropine, and what are their roles?
• List two common side effects of Diphenoxylate with atropine.
• Why is atropine included in this combination medication?

Related terms

Loperamide: An over-the-counter antidiarrheal that works by slowing down gut movement.

Bismuth Subsalicylate: A medication used to treat temporary discomforts of the stomach and gastrointestinal tract, such as diarrhea.

Opioid Agonists: A class of drugs that bind to opioid receptors in the brain to produce pain relief and other effects.