Dihydroxy-vitamin D3
from class: Pharmacology for Nurses Definition Dihydroxy-vitamin D3, also known as calcitriol, is the active form of vitamin D. It plays a crucial role in calcium and phosphate metabolism in the body.
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Predict what's on your test 5 Must Know Facts For Your Next Test Calcitriol increases calcium absorption in the intestines. It is used clinically to treat conditions like hypocalcemia and osteoporosis. Calcitriol helps regulate parathyroid hormone (PTH) levels. It is synthesized in the kidneys from its precursor, 25-hydroxyvitamin D3. Overdose of calcitriol can lead to hypercalcemia, which presents with symptoms such as nausea and weakness. Review Questions What is the primary function of dihydroxy-vitamin D3 in the body? Which organ is responsible for converting vitamin D into its active form, calcitriol? What are some clinical uses of calcitriol?
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