Desiccated thyroid extract is a natural thyroid hormone replacement derived from porcine thyroid glands. It contains both thyroxine (T4) and triiodothyronine (T3).
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Desiccated thyroid extract is used to treat hypothyroidism.
It provides a combination of T4 and T3 hormones, unlike synthetic levothyroxine which contains only T4.
Dosage of desiccated thyroid extract is measured in grains, with one grain roughly equivalent to 60-65 mg.
Patients on desiccated thyroid extract should have their serum TSH, T4, and T3 levels monitored regularly to ensure proper dosing.
Potential side effects include symptoms of hyperthyroidism such as palpitations, weight loss, and anxiety if overdosed.
Review Questions
What hormones are present in desiccated thyroid extract?
How does the composition of desiccated thyroid extract differ from synthetic levothyroxine?
What are common side effects associated with an overdose of desiccated thyroid extract?
Related terms
Levothyroxine: A synthetic form of thyroxine (T4) used as a hormone replacement for hypothyroidism.
Hypothyroidism: A condition where the thyroid gland does not produce enough hormones, leading to symptoms like fatigue and weight gain.
Triiodothyronine (T3): An active thyroid hormone that plays a critical role in metabolism and is present in both natural and synthetic hormone replacements.