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DDAVP

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Pharmacology for Nurses

Definition

DDAVP (Desmopressin) is a synthetic analog of the natural hormone vasopressin, used primarily to treat conditions like diabetes insipidus and bedwetting. It helps reduce urine production by increasing water reabsorption in the kidneys.

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5 Must Know Facts For Your Next Test

  1. DDAVP mimics the action of vasopressin, an antidiuretic hormone produced by the hypothalamus and released by the pituitary gland.
  2. It is commonly used to manage central diabetes insipidus, a condition characterized by excessive thirst and urination.
  3. DDAVP can be administered via various routes including oral tablets, nasal spray, and injection.
  4. The drug works by binding to V2 receptors in the renal collecting ducts, promoting water reabsorption back into the bloodstream.
  5. Common side effects include headaches, nausea, and potential hyponatremia due to water retention.

Review Questions

  • What are the primary medical conditions treated with DDAVP?
  • How does DDAVP function at a cellular level to reduce urine production?
  • What are some common side effects associated with DDAVP usage?

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