Colestipol is a bile acid sequestrant used to lower cholesterol levels in the blood. It binds to bile acids in the intestine, preventing their reabsorption and promoting their excretion.
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Colestipol is primarily used to treat hypercholesterolemia.
It works by binding to bile acids, which are made from cholesterol, leading to increased excretion of these acids.
Common side effects include constipation, bloating, and gastrointestinal discomfort.
Colestipol can interfere with the absorption of other medications; hence, other drugs should be taken at least one hour before or four hours after colestipol administration.
It is available in both tablet and granule form for oral administration.
Review Questions
What is the primary mechanism by which colestipol lowers cholesterol levels?
Name two common side effects associated with colestipol use.
How should colestipol be administered in relation to other medications?
Related terms
Cholestyramine: Another bile acid sequestrant used for lowering cholesterol.
Fibrates: A class of lipid-lowering drugs that primarily reduce triglycerides.
Niacin: A B-vitamin used at high doses to lower LDL cholesterol and raise HDL cholesterol.