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Class IV antiarrhythmic

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Pharmacology for Nurses

Definition

Class IV antiarrhythmics are calcium channel blockers used to treat cardiac arrhythmias. They work by inhibiting the influx of calcium ions during cardiac depolarization, which slows down the heart rate.

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5 Must Know Facts For Your Next Test

  1. Class IV antiarrhythmics primarily include verapamil and diltiazem.
  2. They are most effective in treating supraventricular tachycardias (SVTs).
  3. These drugs can decrease myocardial oxygen demand and prevent angina.
  4. Common side effects include bradycardia, hypotension, and constipation.
  5. They should be used cautiously in patients with heart failure due to their negative inotropic effects.

Review Questions

  • What is the primary mechanism of action for Class IV antiarrhythmics?
  • Name two medications that are classified as Class IV antiarrhythmics.
  • Why should Class IV antiarrhythmics be used cautiously in patients with heart failure?

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