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Cinvanti

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Pharmacology for Nurses

Definition

Cinvanti is an antiemetic medication used to prevent nausea and vomiting caused by chemotherapy. It works by blocking neurokinin-1 (NK1) receptors in the brain.

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5 Must Know Facts For Your Next Test

  1. Cinvanti contains the active ingredient aprepitant, which is a substance P/neurokinin-1 (NK1) receptor antagonist.
  2. It is administered intravenously and is often part of a combination therapy with other antiemetics like 5-HT3 antagonists and corticosteroids.
  3. Common side effects include fatigue, diarrhea, and dizziness.
  4. Cinvanti helps manage both acute and delayed phases of chemotherapy-induced nausea and vomiting (CINV).
  5. The medication should be given prior to the start of chemotherapy to maximize its effectiveness.

Review Questions

  • What is the primary mechanism of action for Cinvanti in preventing nausea and vomiting?
  • List at least two common side effects associated with Cinvanti.
  • When should Cinvanti be administered in relation to chemotherapy treatment?

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