Biologics

Definition

Biologics are complex drugs derived from living organisms, used to treat various medical conditions. They include proteins, nucleic acids, or cells that mimic natural substances in the body.

5 Must Know Facts For Your Next Test

1. Biologics are often used to treat autoimmune diseases, cancers, and some infectious diseases.
2. They are typically administered via injection or infusion due to their large molecular size and sensitivity to digestion.
3. Monoclonal antibodies are a common type of biologic that targets specific cells in the immune system.
4. The production of biologics involves biotechnology and recombinant DNA technology.
5. Biologics are distinct from traditional small-molecule drugs in terms of their complexity and manufacturing process.

Review Questions

• What makes biologics different from traditional small-molecule drugs?
• Why are biologics usually administered via injection or infusion?
• Name one common application of monoclonal antibodies as a type of biologic.

Related terms

Immunosuppressants:

Drugs that inhibit or prevent activity of the immune system.

Monoclonal Antibodies:

Laboratory-made molecules engineered to serve as substitute antibodies that can restore, enhance, or mimic the immune system's attack on cells.

Biosimilar Drugs:

Drugs highly similar to an already approved biological product with no clinically meaningful differences in terms of safety and effectiveness.