Biologic DMARDs

Definition

Biologic DMARDs (Disease-Modifying Antirheumatic Drugs) are a class of medications that target specific components of the immune system to reduce inflammation and halt disease progression in autoimmune conditions. They are often used when traditional DMARDs are ineffective.

5 Must Know Facts For Your Next Test

1. Biologic DMARDs target specific molecules such as TNF-alpha, IL-6, and B cells involved in the inflammatory process.
2. Commonly used biologic DMARDs include infliximab, adalimumab, and etanercept.
3. They are typically administered via injection or infusion rather than oral ingestion.
4. Biologic DMARDs can increase the risk of infections due to their immunosuppressive effects.
5. Patients on biologic DMARDs often require regular monitoring for potential side effects like liver damage and blood disorders.

Review Questions

• What is the primary mechanism of action for biologic DMARDs?
• Name two common biologic DMARDs and their routes of administration.
• What are some potential risks associated with the use of biologic DMARDs?

Related terms

Traditional DMARDs: Medications used to treat autoimmune diseases by broadly suppressing the immune system.

TNF-alpha Inhibitors: A subclass of biologic DMARDs that specifically target and inhibit tumor necrosis factor-alpha.

Autoimmune Diseases: Conditions where the immune system mistakenly attacks the body's own tissues, causing inflammation and tissue damage.