Antigout drugs

Definition

Antigout drugs are medications used to treat gout, a type of arthritis caused by the accumulation of uric acid crystals in joints. These drugs work by reducing inflammation and lowering uric acid levels in the blood.

5 Must Know Facts For Your Next Test

1. Colchicine is an antigout drug that reduces inflammation by inhibiting microtubule formation.
2. Allopurinol decreases uric acid production and is commonly used for long-term management of gout.
3. Probenecid enhances the excretion of uric acid by the kidneys and is often prescribed alongside other antigout medications.
4. NSAIDs like indomethacin can also be used to manage acute gout attacks due to their anti-inflammatory properties.
5. Patients on antigout therapy should avoid alcohol and foods high in purines to prevent exacerbation of symptoms.

Review Questions

• What is the mechanism of action for colchicine in treating gout?
• How does allopurinol help manage chronic gout?
• Why should patients taking antigout drugs avoid alcohol?

Related terms

NSAIDs: Nonsteroidal anti-inflammatory drugs used to reduce inflammation and pain.

Uric Acid: A waste product formed from the breakdown of purines, high levels can lead to gout.

Arthritis: Inflammation of joints that causes pain and stiffness, including conditions like gout.