Amantadine is an antiviral medication that also has efficacy in treating symptoms of Parkinson's disease and drug-induced extrapyramidal reactions. It works by increasing dopamine release and blocking NMDA receptors.
5 Must Know Facts For Your Next Test
Amantadine can help reduce tremors, rigidity, and bradykinesia in Parkinson's disease patients.
It may cause side effects such as dizziness, insomnia, and hallucinations.
Amantadine's mechanism involves both dopaminergic effects and NMDA receptor antagonism.
The drug is often used as an adjunct therapy with other anti-Parkinsonian medications like levodopa.
Caution is required when prescribing Amantadine to elderly patients due to increased risk of cognitive impairment.
Review Questions
What are the primary symptoms of Parkinson's disease that Amantadine helps alleviate?
How does Amantadine exert its therapeutic effects in the brain?
What are some common side effects associated with Amantadine use?
Related terms
Levodopa: A precursor to dopamine used as a primary treatment for Parkinson's disease.
Dopamine Agonists: Medications that mimic dopamine activity in the brain, used in Parkinson’s treatment.
NMDA Receptor Antagonists: Drugs that block NMDA receptors to reduce excitotoxicity, relevant in various neurological conditions.