Alfuzosin

Definition

Alfuzosin is an alpha-1 adrenergic receptor antagonist used to treat the symptoms of benign prostatic hyperplasia (BPH) by relaxing the muscles in the prostate and bladder neck, making it easier to urinate. It does not shrink the prostate but helps relieve urinary symptoms.

5 Must Know Facts For Your Next Test

1. Alfuzosin primarily targets alpha-1 receptors in the lower urinary tract.
2. It is often prescribed for men with BPH to improve urine flow and reduce symptoms of urinary retention.
3. Common side effects include dizziness, headache, and fatigue due to its vasodilatory effects.
4. Alfuzosin should be taken after meals to enhance absorption and reduce the risk of orthostatic hypotension.
5. Contraindications include severe hepatic impairment and concurrent use with other potent CYP3A4 inhibitors.

Review Questions

• What is Alfuzosin used to treat?
• Why should Alfuzosin be taken after meals?
• What are common side effects associated with Alfuzosin?

Related terms

Tamsulosin: Another alpha-1 blocker used for relieving urinary symptoms in BPH.

Finasteride: A 5-alpha-reductase inhibitor that reduces prostate size by blocking testosterone conversion.

Doxazosin: An alpha-1 blocker also used to treat hypertension along with BPH symptoms.