Advil is a brand name for ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID) used to reduce fever, pain, and inflammation. It works by inhibiting the production of prostaglandins, chemicals in the body that promote inflammation and pain.
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Advil is commonly used to treat conditions like headaches, toothaches, menstrual cramps, muscle aches, minor arthritis, and other minor aches and pains.
It works by blocking the enzyme cyclooxygenase (COX), which results in decreased synthesis of prostaglandins.
Advil can cause gastrointestinal side effects such as stomach pain, heartburn, ulcers, and bleeding.
Patients with a history of cardiovascular disease should use Advil with caution as it may increase the risk of heart attack or stroke.
It is important to avoid using Advil concurrently with other NSAIDs or high doses for long periods to prevent adverse effects.
Review Questions
What is the primary mechanism of action for Advil?
List two common side effects associated with prolonged use of Advil.
Why should patients with cardiovascular disease use Advil cautiously?
Related terms
NSAID: A class of drugs that provide analgesic and anti-inflammatory effects by inhibiting cyclooxygenase enzymes.
Prostaglandins: Lipid compounds that have hormone-like effects and play a role in inflammation and pain.
Cyclooxygenase (COX): An enzyme responsible for forming prostanoids, including thromboxane and prostaglandins which are involved in inflammation and pain.