Activated clotting time (ACT)
Definition
Activated clotting time (ACT) is a test that measures the time it takes for blood to clot in the presence of an activator. It is commonly used to monitor high-dose heparin therapy during procedures such as cardiac surgery.
5 Must Know Facts For Your Next Test
- ACT is used to monitor anticoagulation effects during surgeries and invasive procedures.
- High-dose heparin therapy requires frequent monitoring using ACT to ensure therapeutic levels are maintained.
- An abnormal ACT result can indicate either excessive anticoagulation or insufficient anticoagulation, requiring dosage adjustments.
- The normal range for ACT varies depending on the procedure and the patient's baseline levels.
- Point-of-care devices are often used for rapid ACT testing in clinical settings.
Review Questions
- What is the primary purpose of measuring Activated Clotting Time (ACT)?
- Why is ACT particularly important during cardiac surgery?
- How does an abnormal ACT result influence patient care during high-dose heparin therapy?
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Related terms
Heparin: An anticoagulant medication used to prevent and treat blood clots.
Prothrombin Time (PT): A test that measures how long it takes for blood plasma to clot, commonly used to monitor warfarin therapy.
Partial Thromboplastin Time (PTT): A test that measures the time it takes for blood to clot, often used to evaluate intrinsic pathway coagulation factors and monitor heparin therapy.
