Acetazolamide
Definition
Acetazolamide is a carbonic anhydrase inhibitor used to reduce fluid build-up and pressure in conditions like glaucoma and intracranial hypertension. It is also used to treat certain types of seizures and altitude sickness.
5 Must Know Facts For Your Next Test
- Acetazolamide decreases the production of cerebrospinal fluid, which helps lower intracranial pressure.
- It is often used as an adjunct treatment for epilepsy when other medications are insufficient.
- Common side effects include metabolic acidosis, hypokalemia, and paresthesia.
- Acetazolamide can induce diuresis leading to electrolyte imbalances; monitoring of electrolyte levels is essential during treatment.
- The drug interacts with salicylates, which can increase the risk of toxicity.
Review Questions
- What primary mechanism does acetazolamide use to lower intracranial pressure?
- List three common side effects associated with acetazolamide use.
- How does acetazolamide interact with salicylates, and why is this clinically significant?
"Acetazolamide" appears in:
Related terms
Carbonic Anhydrase Inhibitors: A class of drugs that reduce fluid build-up by inhibiting the enzyme carbonic anhydrase.
Intracranial Hypertension: A condition characterized by increased pressure within the skull.
Diuretics: Medications that promote diuresis, or increased urine production.
